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« Lower Doses of Genentech's Avastin® Effective in Treating Lung Cancer | Main | Conference & CLE Calendar »

February 23, 2007


Readers interested in this subject might also be interested in taking a look at my web Journal. Since January 2006, I have been following and writing about Avastin and Lucentis, most recently reporting on the February 22nd front page story about these drugs appearing in the WSJ.

Prior to that, I posted a White Paper about the controversy, written by a group of retinal specialists (identified at the end of the piece). In all, I have now posted 13 stories about Avastin and Avastin vs Lucentis.

Please see my web Journal at:


Irv Arons

Here is a great audio interview with the director of health policy at the American Academy of Opthalmology on the head to head trial of Lucentis vs. Avastin:


My father has wet ALMG and Dry ALMG. In the absence of treatmetn he was discharged 4 years ago and is now blind in one eye but has recently been re-admitted to consider treatment for his other eye with Dry ALMG now showing signs of the WET condtion. He is now being considered to retain his reamining sight with Lucentis on NHS which looks unlikely - If this fails where can I obtain for him treatment with Avastin

I was diagnosed with dry macular in Nov. and taking eye vitamins daily but this week having trouble seeing clocks and even reading large print books. Dr. exam shows bleeding in one eye and scheduled injections.I have to dedide avastin or lucentis. please tell me if its possible to change from dry to wet/

My diagnose was and still is AMD wet form, 1 month ago i agreed to make injection of avastin. My current doctors were recommending me to make the second injection of Avastin at the end of October, but i am really afraid that it'd not help me and therefore i am planning to show my eyes to alternative clinic, which primary treatment of AMD is Lucentis. I heard that Lucentis is better and more effective to use after injection of Avastin (Munich-base study). Did somebody provide an injection of Lucentis after provision of injection of avastin? I'd really appreciate for any feedback.

How does one prevent dry macular degeneration becoming wet?

Dear Pat:

First, a disclaimer: while we are the Patent Docs, none of us are medical doctors or ophthamologists, so whatever you read here should not be used in lieu of speaking with a doctor if you are having vision problems.

But in an effort to be helpful, here is the definition of "wet" and "dry" macular degeneration from wikipedia.com:

The inner layer of the eye is the retina, which contains nerves that communicate sight, and behind the retina is the choroid, which contains the blood supply to the retina. In the dry (nonexudative) form, cellular debris called drusen accumulate between the retina and the choroid, and the retina can become detached. In the wet (exudative) form, which is more severe, blood vessels grow up from the choroid behind the retina, and the retina can also become detached. It can be treated with laser coagulation, and with medication that stops and sometimes reverses the growth of blood vessels.[1][2]

You might also look at the Amnerican Macular Degeneration Foundation website at www.macular.org.

Hope this helps.

I have had 25 injections of Avastin for wet type, and my retina specialist is considering an every 4 week trial of Avastin for 4 treatments, then 4 of Lucentis, to see if an impprovement shows. I must say that the Avastin did curb the progression, and now hope an even better improvement with this trial.

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